Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey
Identifieur interne : 002396 ( Main/Exploration ); précédent : 002395; suivant : 002397Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey
Auteurs : John J. Mcgrath ; Sukanta Saha ; Ali O. Al-Hamzawi [Iraq] ; Jordi Alonso [Espagne] ; Laura Andrade [Brésil] ; Guilherme Borges [Mexique] ; Evelyn J. Bromet ; Mark Oakley Browne [Australie] ; Ronny Bruffaerts [Belgique] ; Jose M. Caldas De Almeida [Portugal] ; John Fayyad [Liban] ; Silvia Florescu [Roumanie] ; Giovanni De Girolamo [Italie] ; Oye Gureje [Nigeria] ; Chiyi Hu [République populaire de Chine] ; Peter De Jonge [Pays-Bas] ; Viviane Kovess-Masfety [France] ; Jean Pierre Lepine [France] ; Carmen C. W. Lim [Nouvelle-Zélande] ; Fernando Navarro-Mateu [Espagne] ; Maria Piazza [Pérou] ; Nancy Sampson ; José Posada-Villa [Colombie] ; Kenneth S. Kendler [États-Unis] ; Ronald C. KesslerSource :
- Schizophrenia Bulletin [ 0586-7614 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
- épidémiologie : Troubles psychotiques.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Mâle, Prévalence, Risque, Santé mentale, Santé mondiale, Sujet âgé, Âge de début.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Psychotic Disorders.
- statistics & numerical data : Global Health, Mental Health.
- Adolescent, Adult, Age of Onset, Aged, Female, Humans, Male, Middle Aged, Prevalence, Risk, Young Adult.
Abstract
Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features.
Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency.
Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17–41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (
While most people with lifetime PEs have first onsets in adolescence or young adulthood, projected estimates indicate that nearly a quarter of first onsets occur after age 40 years. The extent to which late onset PEs are associated with (a) late onset mental disorders or (b) declining cognitive and/or sensory function need further research.
Url:
DOI: 10.1093/schbul/sbw011
PubMed: 27038468
PubMed Central: 4903064
Affiliations:
- Australie, Belgique, Brésil, Colombie, Espagne, France, Iraq, Italie, Liban, Mexique, Nigeria, Nouvelle-Zélande, Pays-Bas, Portugal, Pérou, Roumanie, République populaire de Chine, États-Unis
- Virginie
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Caldas De Almeida</name><affiliation wicri:level="1"><nlm:aff id="AF0011"><institution>Chronic Diseases Research Center (CEDOC) and Department of Mental Health, Faculdade de Ciências Médicas, Universidade Nova de Lisboa</institution>,<addr-line>Lisbon</addr-line>,<country>Portugal</country>;</nlm:aff><country xml:lang="fr">Portugal</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name><affiliation wicri:level="1"><nlm:aff id="AF0012"><institution>Institute for Development, Research, Advocacy and Applied Care (IDRAAC)</institution>,<addr-line>Beirut</addr-line>,<country>Lebanon</country>;</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name><affiliation wicri:level="1"><nlm:aff id="AF0013"><institution>National School of Public Health, Management and Professional Development</institution>,<addr-line>Bucharest</addr-line>,<country>Romania</country>;</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name><affiliation wicri:level="1"><nlm:aff id="AF0014"><institution>IRCCS St John of God Clinical Research Centre/IRCCS Centro S. Giovanni di Dio Fatebenefratelli</institution>,<addr-line>Brescia</addr-line>,<country>Italy</country>;</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name><affiliation wicri:level="1"><nlm:aff id="AF0015"><institution>Department of Psychiatry, University College Hospital</institution>,<addr-line>Ibadan</addr-line>,<country>Nigeria</country>;</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name><affiliation wicri:level="1"><nlm:aff id="AF0016"><institution>Shenzhen Institute of Mental Health & Shenzhen Kanging Hospital</institution>,<addr-line>Shenzhen</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name><affiliation wicri:level="1"><nlm:aff id="AF0017"><institution>Department of Psychiatry, Interdisciplinary Center, Psychopathology and Emotion Regulation (ICPE), University Medical Center Groningen, University of Groningen</institution>,<addr-line>Groningen</addr-line>,<country>The Netherlands</country>;</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name><affiliation wicri:level="1"><nlm:aff id="AF0018"><institution>Ecole des Hautes Etudes en Santé Publique (EHESP), Paris Descartes University</institution>,<addr-line>Paris</addr-line>,<country>France</country>;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lepine, Jean Pierre" sort="Lepine, Jean Pierre" uniqKey="Lepine J" first="Jean Pierre" last="Lepine">Jean Pierre Lepine</name><affiliation wicri:level="1"><nlm:aff id="AF0019"><institution>Hôpital Lariboisière Fernand Widal, Assistance Publique Hôpitaux de Paris INSERM UMR-S 1144, University Paris Diderot and Paris Descartes Paris</institution>,<addr-line>Paris</addr-line>,<country>France</country>;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lim, Carmen C W" sort="Lim, Carmen C W" uniqKey="Lim C" first="Carmen C. W." last="Lim">Carmen C. W. Lim</name><affiliation wicri:level="1"><nlm:aff id="AF0020"><institution>Department of Psychological Medicine, Dunedin School of Medicine, University of Otago</institution>,<addr-line>Dunedin</addr-line>,<country>New Zealand</country>;</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Navarro Mateu, Fernando" sort="Navarro Mateu, Fernando" uniqKey="Navarro Mateu F" first="Fernando" last="Navarro-Mateu">Fernando Navarro-Mateu</name><affiliation wicri:level="1"><nlm:aff id="AF0021"><institution>IMIB-Arrixaca, CIBERESP-Murcia, Subdirección General de Salud Mental y Asistencia Psiquiátrica, Servicio Murciano de Salud, El Palmar (Murcia)</institution>,<addr-line>Murcia</addr-line>,<country>Spain</country>;</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Piazza, Maria" sort="Piazza, Maria" uniqKey="Piazza M" first="Maria" last="Piazza">Maria Piazza</name><affiliation wicri:level="1"><nlm:aff id="AF0022"><institution>National Institute of Health, Peru, Universidad Cayetano Hereidia</institution>,<addr-line>Lima</addr-line>,<country>Peru</country>;</nlm:aff><country xml:lang="fr">Pérou</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name><affiliation><nlm:aff id="AF0023"><institution>Department of Health Care Policy, Harvard University</institution>,<addr-line>Boston, MA</addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="José" last="Posada-Villa">José Posada-Villa</name><affiliation wicri:level="1"><nlm:aff id="AF0024"><institution>El Bosque University</institution>,<addr-line>Bogota</addr-line>,<country>Colombia</country>;</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name><affiliation wicri:level="2"><nlm:aff id="AF0025"><institution>Department of Psychiatry, Virginia Commonwealth University</institution>,<addr-line>Richmond, VA</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Richmond</wicri:cityArea></affiliation></author><author><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. 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Mcgrath</name></author><author><name sortKey="Saha, Sukanta" sort="Saha, Sukanta" uniqKey="Saha S" first="Sukanta" last="Saha">Sukanta Saha</name></author><author><name sortKey="Al Hamzawi, Ali O" sort="Al Hamzawi, Ali O" uniqKey="Al Hamzawi A" first="Ali O." last="Al-Hamzawi">Ali O. Al-Hamzawi</name><affiliation wicri:level="1"><nlm:aff id="AF0004"><institution>Department of Psychiatry, College of Medicine, Qadisia University</institution>,<addr-line>Diwania Province</addr-line>,<country>Iraq</country>;</nlm:aff><country xml:lang="fr">Iraq</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alonso, Jordi" sort="Alonso, Jordi" uniqKey="Alonso J" first="Jordi" last="Alonso">Jordi Alonso</name><affiliation wicri:level="1"><nlm:aff id="AF0005"><institution>IMIM-Hospital del Mar Medical Research Institute, Parc de Salut Mar, Barcelona, Spain; Pompeu Fabra University (UPF), Barcelona, Spain; and CIBER en Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>;</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Andrade, Laura" sort="Andrade, Laura" uniqKey="Andrade L" first="Laura" last="Andrade">Laura Andrade</name><affiliation wicri:level="1"><nlm:aff id="AF0006"><institution>Department/Institute of Psychiatry, University of Sao Paulo Medical School</institution>,<addr-line>Sao Paulo</addr-line>,<country>Brazil</country>;</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Borges, Guilherme" sort="Borges, Guilherme" uniqKey="Borges G" first="Guilherme" last="Borges">Guilherme Borges</name><affiliation wicri:level="1"><nlm:aff id="AF0007"><institution>National Institute of Psychiatry, Mexico City, Mexico and Metropolitan Autonomous University</institution>,<addr-line>Mexico City</addr-line>,<country>Mexico</country>;</nlm:aff><country xml:lang="fr">Mexique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bromet, Evelyn J" sort="Bromet, Evelyn J" uniqKey="Bromet E" first="Evelyn J." last="Bromet">Evelyn J. Bromet</name><affiliation><nlm:aff id="AF0008"><institution>Department of Psychiatry, Stony Brook University School of Medicine</institution>,<addr-line>Stony Brook, NY</addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Oakley Browne, Mark" sort="Oakley Browne, Mark" uniqKey="Oakley Browne M" first="Mark" last="Oakley Browne">Mark Oakley Browne</name><affiliation wicri:level="1"><nlm:aff id="AF0009"><institution>Centre for Mental Health, University of Melbourne</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>;</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bruffaerts, Ronny" sort="Bruffaerts, Ronny" uniqKey="Bruffaerts R" first="Ronny" last="Bruffaerts">Ronny Bruffaerts</name><affiliation wicri:level="1"><nlm:aff id="AF0010"><institution>Universitair Psychiatrisch Centrum—Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg</institution>,<addr-line>Leuvan</addr-line>,<country>Belgium</country>;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Caldas De Almeida, Jose M" sort="Caldas De Almeida, Jose M" uniqKey="Caldas De Almeida J" first="Jose M." last="Caldas De Almeida">Jose M. Caldas De Almeida</name><affiliation wicri:level="1"><nlm:aff id="AF0011"><institution>Chronic Diseases Research Center (CEDOC) and Department of Mental Health, Faculdade de Ciências Médicas, Universidade Nova de Lisboa</institution>,<addr-line>Lisbon</addr-line>,<country>Portugal</country>;</nlm:aff><country xml:lang="fr">Portugal</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name><affiliation wicri:level="1"><nlm:aff id="AF0012"><institution>Institute for Development, Research, Advocacy and Applied Care (IDRAAC)</institution>,<addr-line>Beirut</addr-line>,<country>Lebanon</country>;</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name><affiliation wicri:level="1"><nlm:aff id="AF0013"><institution>National School of Public Health, Management and Professional Development</institution>,<addr-line>Bucharest</addr-line>,<country>Romania</country>;</nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name><affiliation wicri:level="1"><nlm:aff id="AF0014"><institution>IRCCS St John of God Clinical Research Centre/IRCCS Centro S. Giovanni di Dio Fatebenefratelli</institution>,<addr-line>Brescia</addr-line>,<country>Italy</country>;</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name><affiliation wicri:level="1"><nlm:aff id="AF0015"><institution>Department of Psychiatry, University College Hospital</institution>,<addr-line>Ibadan</addr-line>,<country>Nigeria</country>;</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name><affiliation wicri:level="1"><nlm:aff id="AF0016"><institution>Shenzhen Institute of Mental Health & Shenzhen Kanging Hospital</institution>,<addr-line>Shenzhen</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name><affiliation wicri:level="1"><nlm:aff id="AF0017"><institution>Department of Psychiatry, Interdisciplinary Center, Psychopathology and Emotion Regulation (ICPE), University Medical Center Groningen, University of Groningen</institution>,<addr-line>Groningen</addr-line>,<country>The Netherlands</country>;</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name><affiliation wicri:level="1"><nlm:aff id="AF0018"><institution>Ecole des Hautes Etudes en Santé Publique (EHESP), Paris Descartes University</institution>,<addr-line>Paris</addr-line>,<country>France</country>;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lepine, Jean Pierre" sort="Lepine, Jean Pierre" uniqKey="Lepine J" first="Jean Pierre" last="Lepine">Jean Pierre Lepine</name><affiliation wicri:level="1"><nlm:aff id="AF0019"><institution>Hôpital Lariboisière Fernand Widal, Assistance Publique Hôpitaux de Paris INSERM UMR-S 1144, University Paris Diderot and Paris Descartes Paris</institution>,<addr-line>Paris</addr-line>,<country>France</country>;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lim, Carmen C W" sort="Lim, Carmen C W" uniqKey="Lim C" first="Carmen C. W." last="Lim">Carmen C. W. Lim</name><affiliation wicri:level="1"><nlm:aff id="AF0020"><institution>Department of Psychological Medicine, Dunedin School of Medicine, University of Otago</institution>,<addr-line>Dunedin</addr-line>,<country>New Zealand</country>;</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Navarro Mateu, Fernando" sort="Navarro Mateu, Fernando" uniqKey="Navarro Mateu F" first="Fernando" last="Navarro-Mateu">Fernando Navarro-Mateu</name><affiliation wicri:level="1"><nlm:aff id="AF0021"><institution>IMIB-Arrixaca, CIBERESP-Murcia, Subdirección General de Salud Mental y Asistencia Psiquiátrica, Servicio Murciano de Salud, El Palmar (Murcia)</institution>,<addr-line>Murcia</addr-line>,<country>Spain</country>;</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Piazza, Maria" sort="Piazza, Maria" uniqKey="Piazza M" first="Maria" last="Piazza">Maria Piazza</name><affiliation wicri:level="1"><nlm:aff id="AF0022"><institution>National Institute of Health, Peru, Universidad Cayetano Hereidia</institution>,<addr-line>Lima</addr-line>,<country>Peru</country>;</nlm:aff><country xml:lang="fr">Pérou</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name><affiliation><nlm:aff id="AF0023"><institution>Department of Health Care Policy, Harvard University</institution>,<addr-line>Boston, MA</addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="José" last="Posada-Villa">José Posada-Villa</name><affiliation wicri:level="1"><nlm:aff id="AF0024"><institution>El Bosque University</institution>,<addr-line>Bogota</addr-line>,<country>Colombia</country>;</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name><affiliation wicri:level="2"><nlm:aff id="AF0025"><institution>Department of Psychiatry, Virginia Commonwealth University</institution>,<addr-line>Richmond, VA</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Richmond</wicri:cityArea></affiliation></author><author><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name><affiliation><nlm:aff id="AF0023"><institution>Department of Health Care Policy, Harvard University</institution>,<addr-line>Boston, MA</addr-line>;</nlm:aff></affiliation></author></analytic><series><title level="j">Schizophrenia Bulletin</title><idno type="ISSN">0586-7614</idno><idno type="eISSN">1745-1701</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Female</term><term>Global Health (statistics & numerical data)</term><term>Humans</term><term>Male</term><term>Mental Health (statistics & numerical data)</term><term>Middle Aged</term><term>Prevalence</term><term>Psychotic Disorders (epidemiology)</term><term>Risk</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Prévalence</term><term>Risque</term><term>Santé mentale ()</term><term>Santé mondiale ()</term><term>Sujet âgé</term><term>Troubles psychotiques (épidémiologie)</term><term>Âge de début</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Psychotic Disorders</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Global Health</term><term>Mental Health</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Troubles psychotiques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Risk</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Prévalence</term><term>Risque</term><term>Santé mentale</term><term>Santé mondiale</term><term>Sujet âgé</term><term>Âge de début</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background:</title><p>Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features.</p></sec><sec><title>Methods:</title><p>Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency.</p></sec><sec><title>Results:</title><p>Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17–41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (<italic>F</italic> = 14.1, <italic>P</italic> < .001) but negatively associated with annualized PE frequency rates (<italic>F</italic> = 8.0, <italic>P</italic> < .001).</p></sec><sec><title>Discussion:</title><p>While most people with lifetime PEs have first onsets in adolescence or young adulthood, projected estimates indicate that nearly a quarter of first onsets occur after age 40 years. The extent to which late onset PEs are associated with (a) late onset mental disorders or (b) declining cognitive and/or sensory function need further research.</p></sec></div></front></TEI><affiliations><list><country><li>Australie</li><li>Belgique</li><li>Brésil</li><li>Colombie</li><li>Espagne</li><li>France</li><li>Iraq</li><li>Italie</li><li>Liban</li><li>Mexique</li><li>Nigeria</li><li>Nouvelle-Zélande</li><li>Pays-Bas</li><li>Portugal</li><li>Pérou</li><li>Roumanie</li><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Virginie</li></region></list><tree><noCountry><name sortKey="Bromet, Evelyn J" sort="Bromet, Evelyn J" uniqKey="Bromet E" first="Evelyn J." last="Bromet">Evelyn J. Bromet</name><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name><name sortKey="Mcgrath, John J" sort="Mcgrath, John J" uniqKey="Mcgrath J" first="John J." last="Mcgrath">John J. Mcgrath</name><name sortKey="Saha, Sukanta" sort="Saha, Sukanta" uniqKey="Saha S" first="Sukanta" last="Saha">Sukanta Saha</name><name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name></noCountry><country name="Iraq"><noRegion><name sortKey="Al Hamzawi, Ali O" sort="Al Hamzawi, Ali O" uniqKey="Al Hamzawi A" first="Ali O." last="Al-Hamzawi">Ali O. Al-Hamzawi</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Alonso, Jordi" sort="Alonso, Jordi" uniqKey="Alonso J" first="Jordi" last="Alonso">Jordi Alonso</name></noRegion><name sortKey="Navarro Mateu, Fernando" sort="Navarro Mateu, Fernando" uniqKey="Navarro Mateu F" first="Fernando" last="Navarro-Mateu">Fernando Navarro-Mateu</name></country><country name="Brésil"><noRegion><name sortKey="Andrade, Laura" sort="Andrade, Laura" uniqKey="Andrade L" first="Laura" last="Andrade">Laura Andrade</name></noRegion></country><country name="Mexique"><noRegion><name sortKey="Borges, Guilherme" sort="Borges, Guilherme" uniqKey="Borges G" first="Guilherme" last="Borges">Guilherme Borges</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Oakley Browne, Mark" sort="Oakley Browne, Mark" uniqKey="Oakley Browne M" first="Mark" last="Oakley Browne">Mark Oakley Browne</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Bruffaerts, Ronny" sort="Bruffaerts, Ronny" uniqKey="Bruffaerts R" first="Ronny" last="Bruffaerts">Ronny Bruffaerts</name></noRegion></country><country name="Portugal"><noRegion><name sortKey="Caldas De Almeida, Jose M" sort="Caldas De Almeida, Jose M" uniqKey="Caldas De Almeida J" first="Jose M." last="Caldas De Almeida">Jose M. Caldas De Almeida</name></noRegion></country><country name="Liban"><noRegion><name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name></noRegion></country><country name="Roumanie"><noRegion><name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name></noRegion></country><country name="Italie"><noRegion><name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name></noRegion></country><country name="Nigeria"><noRegion><name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name></noRegion></country><country name="République populaire de Chine"><noRegion><name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name></noRegion></country><country name="Pays-Bas"><noRegion><name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name></noRegion></country><country name="France"><noRegion><name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name></noRegion><name sortKey="Lepine, Jean Pierre" sort="Lepine, Jean Pierre" uniqKey="Lepine J" first="Jean Pierre" last="Lepine">Jean Pierre Lepine</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Lim, Carmen C W" sort="Lim, Carmen C W" uniqKey="Lim C" first="Carmen C. W." last="Lim">Carmen C. W. Lim</name></noRegion></country><country name="Pérou"><noRegion><name sortKey="Piazza, Maria" sort="Piazza, Maria" uniqKey="Piazza M" first="Maria" last="Piazza">Maria Piazza</name></noRegion></country><country name="Colombie"><noRegion><name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="José" last="Posada-Villa">José Posada-Villa</name></noRegion></country><country name="États-Unis"><region name="Virginie"><name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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